Characterizing the Structure–Function Relationship of a Naturally Occurring RNA Thermometer

Characterizing the Structure-Function Relationship of a Naturally Occurring RNA Thermometer.

A large number of bacteria have been found to govern virulence and heat shock responses using temperature-sensing RNAs known as RNA thermometers. A prime example is the agsA thermometer known to regulate the production of the AgsA heat shock protein in Salmonella enterica using a "fourU" structural motif. Using the SHAPE-Seq RNA structure-probing method in vivo and in vitro, we found that the r...

Thermodynamic characterization of naturally occurring RNA tetraloops.

Although tetraloops are one of the most frequently occurring secondary structure motifs in RNA, less than one-third of the 30 most frequently occurring RNA tetraloops have been thermodynamically characterized. Therefore, 24 stem-loop sequences containing common tetraloops were optically melted, and the thermodynamic parameters DeltaH degrees , DeltaS degrees , DeltaG degrees (37,) and T(M) for ...

the investigation of the relationship between type a and type b personalities and quality of translation

چکیده ندارد.

A naturally occurring DNA-RNA complex from Neurospora crassa.

tcRNA as a naturally occurring antisense RNA in eukaryotes.

Since the formulation of our or ig ina l hypothesis that small RNAs are involved with gene expression by the i r associat ion with mRNAs (1) numerous reports have appeared demonstrating the i r role in processing and t r ansc r ip t ion termination (2,3) as well as regulation of t rans la t ion (4 ,5 ) . In the l a t t e r case i t has been shown in E. co l i t ha t antisense RNAs (complementar...